• Der Internist · May 2012

    [Respiratory pump failure. Clinical symptoms, diagnostics and therapy].

    • M Pfeifer.
    • Zentrum für Pneumologie, Klinik Donaustauf, Ludwigstrasse 68, Donaustauf, Germany. michael.pfeifer@ukr.de
    • Internist (Berl). 2012 May 1;53(5):534-44.

    AbstractThe total anatomical and functional apparatus which allows normal ventilation of the lungs is known as the respiratory pump. An insufficiency of this system, which can be caused by a multitude of reasons, primarily affects the inspiratory musculature and especially the diaphragm. One of the essential clinical characteristics is rapid shallow breathing. Exhaustion of the repiratory musculature due to acute respiratory insufficiency is normally clinically registered but can also be functionally determined in particular by the maximum static inspiratory closed mouth pressure. A further option is invasive measurement of the transdiaphragmal pressure, which however is not suitable as a routine procedure. Mechanical ventilation is used as treatment of respiratory pump insufficiency independent of the cause. This is initially a non-invasive procedure but if unsuccessful intubation and invasive ventilation are indicated. The technical developments in the field of extracorporeal gas exchange systems are very promising. However, in view of the insufficient data, ventilation procedures using masks and tubes still remain the first choice methods.

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