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Randomized Controlled Trial Clinical Trial
Pain relief induced by repetitive transcranial magnetic stimulation of precentral cortex.
- J P Lefaucheur, X Drouot, Y Keravel, and J P Nguyen.
- Services de Physiologie, Explorations Fonctionnelles, Hopital Henri Mondor, 51 avenue de Lattre de Tassigny, 94010 Creteil, France.
- Neuroreport. 2001 Sep 17;12(13):2963-5.
AbstractChronic electrical stimulation of the precentral (motor) cortex using surgically implanted electrodes is performed to treat medication-resistant neurogenic pain. The goal of this placebo-controlled study was to obtain such antalgic effects by means of a non-invasive cortical stimulation using repetitive transcranial magnetic stimulation (rTMS). Eighteen patients with intractable neurogenic pain of various origins were included and underwent a 20 min session of either 10 Hz, 0.5 Hz or* sham rTMS over the motor cortex in a random order. A significant decrease in the mean pain level of the series was obtained only after 10 Hz rTMS. This study shows that a transient pain relief can be induced by 10 Hz rTMS of the motor cortex in some patients suffering from chronic neurogenic pain.
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