• Icten E Ince, Leyla Iyilikci, Sebnem Yilmaz, Dilek Güneş, Muhammed Akkuş, and Duyguhan Isguven.
• Department of Anesthesiology and Intensive Care, Dokuz Eylül University, İzmir, Turkey.
• J. Pediatr. Hematol. Oncol. 2013 Mar 1;35(2):112-7.

IntroductionShort hemato-oncologic procedures are often painful in children, and sedation should be performed outside the operating room.Aim: The study aims to compare the effects of remifentanil with those of fentanyl administered during short hemato-oncologic interventions in children.Materials And MethodsA prospective, randomized study was planned for 29 ASA I to III children (aged, 2 to 18 y) to undergo a total of 60 short oncologic interventions. The patients were placed into 2 groups: propofol-remifentanil (group PR) and propofol-fentanyl (group PF). Group PR was first administered propofol (2 mg/kg) and then remifentanil bolus (0.5 μg/kg). Group PF was first administered propofol (2 mg/kg) and then fentanyl bolus (0.5 μg/kg). Systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, respiratory rate, peripheral oxygen saturation, and heart rate were recorded every 3 minutes during the intervention and every 5 minutes after the operation. Postanesthetic recovery scores, eye-opening time to speech, and recovery time were recorded.ResultsComparison of diastolic arterial pressure in groups at minute 3 of the procedure showed significant difference (P<0.05). Eye-opening to speech (P=0.043) and recovery times (P=0.002) were shorter in group PR.ConclusionsDuring short hemato-oncologic interventions in children, the PR combination is a suitable one for early recovery.

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