• Clin J Pain · Dec 2000

    Case Reports

    Successful treatment of erythromelalgia with intrathecal hydromorphone and clonidine.

    • S Macres and S Richeimer.
    • Department of Anesthesiology, University of California, Sacramento 95817, USA.
    • Clin J Pain. 2000 Dec 1; 16 (4): 310-3.

    ObjectiveThe objective of this study was to determine if intractable pain from erythromelalgia could be successfully treated with intrathecal hydromorphone and clonidine.DesignA single case of pain from erythromelalgia refractory to multiple treatment modalities was examined and treated.SettingThe setting is an outpatient pain clinic at a major university teaching hospital.PatientOur patient is an 82-year-old woman with hypertension and peripheral vascular disease.InterventionIntrathecal opioid and an alpha2-agonist were administered.Outcome MeasuresOutcome was determined by means of patient self-report during office follow-up visits.Results And ConclusionsAdministration of intrathecal opioid and an alpha2-agonist can be effective in the treatment of the pain of erythromelalgia and offers an alternative pain treatment modality for patients with unremitting pain refractory to more conservative therapy.

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