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Expert Opin Pharmacother · Mar 2010
Randomized Controlled Trial Multicenter Study Comparative StudyInsights from the dabigatran versus warfarin in patients with atrial fibrillation (RE-LY) trial.
- Chee W Khoo and Gregory Y H Lip.
- University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham B18 7QH, UK. g.y.h.lip@bham.ac.uk
- Expert Opin Pharmacother. 2010 Mar 1;11(4):685-7.
AbstractOral anticoagulants such as warfarin have been used widely for the treatment of venous thromboembolism and stroke prevention in atrial fibrillation (AF) patients. Warfarin has significant limitations and also requires frequent monitoring. Thus, there is an unmet need, with the quest for alternative oral anticoagulants with stable pharmacokinetics and pharmacodynamics that do not need monitoring. The paper under evaluation provides us with up-to-date information on the safety and efficacy of a new oral anticoagulant, dabigatran, compared with warfarin for stroke prevention in AF patients.
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