• Paediatric anaesthesia · Mar 2003

    Randomized Controlled Trial Clinical Trial

    Caudal bupivacaine and s(+)-ketamine for postoperative analgesia in children.

    • Frank Weber and Hinnerk Wulf.
    • Department of Anaesthesia, University of Regensburg, Regensburg, Germany. frank.weber@klinik.uni-regensburg.de
    • Paediatr Anaesth. 2003 Mar 1; 13 (3): 244-8.

    BackgroundThe aim of this study was to evaluate whether caudal s-ketamine would prolong analgesia together with caudal bupivacaine.MethodsThirty children, ASA I-II, 1 month-9 years, scheduled for minor inguinal or penile surgery, were randomly assigned in a prospective, double-blind fashion to receive single shot caudal blockade by either bupivacaine 0.125% 1 ml.kg(-1) (group B, n = 15) or a mixture of bupivacaine 0.125% 1 ml.kg(-1) and preservative-free s-ketamine 0.5 mg.kg(-1) (group K, n = 15). Postoperative pain was assessed by means of an observational 10-point scoring system and analgesia was administered if the pain score exceeded a value of 3.ResultsWithin 24 h after caudal block 10 patients (67%) in group K and three patients in group B (20%) did not require additional analgesic medication (P < 0.01). There were no significant differences between the groups for incidence of haemodynamic changes. We did not observe any negative side-effects attributable to the caudal block or s-ketamine.ConclusionsAddition of preservative-free s-ketamine 0.5 mg.kg(-1) to caudal bupivacaine 0.125% 1 ml.kg(-1) provides significant prolongation of analgesia without producing negative side-effects.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…