• Pain · Jan 2006

    Clinical Trial

    Deep brain stimulation for the alleviation of post-stroke neuropathic pain.

    • Sarah L F Owen, Alexander L Green, John F Stein, and Tipu Z Aziz.
    • University Laboratory of Physiology, University of Oxford, UK.
    • Pain. 2006 Jan 1;120(1-2):202-6.

    AbstractOur aim was to asses the efficacy of deep brain stimulation in post-stroke neuropathic pain. Since 2000, 15 patients with post-stroke intractable neuropathic pain were treated with deep brain stimulation of the periventricular gray area (PVG), sensory thalamus (Ventroposterolateral nucleus-VPL) or both. Pain was assessed using both a visual analogue scale and the McGill's pain questionnaire. VAS scores show a mean improvement of 48.8% (SD 8.6%). However, there is a wide variation between patients. This study demonstrates that it is an effective treatment in 70% of such patients.

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