• S Iribarren-Diarasarri, F Aizpuru-Barandiaran, T Muñoz-Martínez, J L Dudagoitia-Otaolea, A Castañeda-Sáez, M Hernández-López, S Martínez-Alutiz, C Vinuesa-Lozano, and N Aretxabala-Kortajarena.
• Unidad de Medicina Intensiva. Hospital Txagorritxu. Vitoria. Alava. España. SEBASTIAN.IRIBARRENDIARASARRI@osakidetza.net
• Med Intensiva. 2009 Apr 1; 33 (3): 115-22.

ObjectiveTo determine the changes in the health-related quality of life (hRQOL) six months after discharge from the ICU and the conditions associated to them.DesignA prospective cohort study.Setting14 beds medical-surgical intensive care unit (ICU).PatientsA total of 247 patients admitted to our ICU for more than 24 hours with a follow-up of 6 months were study. Those admitted with acute coronary syndrome or for monitoring purposes were excluded.InterventionA quality of life survey was conducted using the score developed by the PAEEC group (project of the epidemiological analysis of critical illness) to assess hRQOL before ICU admission and 6 months after discharge.ResultsThe hRQOL deteriorated, going from a median value of 3 to 6 (p < 0.001). The multivariate analysis showed less deterioration of hRQOL in patients with chronic health conditions registered on the APAChE-II score (regression coefficient [RC] = -1.4; 95% CI, -2.5 to -0.2; p < 0.02) and in those with a hRQOL > or = 10 points (RC = -4,4; 95% CI, -5.9 to -2.8; p < 0.001). There was more deterioration in polytraumatized patients (RC = 1.9; 95% CI, 0.6-3.3; p = 0.01) or with renal failure (RC = 3.9; 95% CI, 1.9-5.9; p < 0.001) or in those with a stay duration longer than 10 days (RC = 1.9; 95% CI, 0.6-3.2; p < 0.001).ConclusionsMost patients experience deterioration of hRQOL. Patients with chronic diseases or with worst previous hRQOL who survive 6 months experience less deterioration of hRQOL than those who are polytraumatized or have renal failure or a longer ICU stay.

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