• Surg Laparosc Endosc Percutan Tech · Dec 2008

    Review Meta Analysis

    Effect of heated and humidified carbon dioxide on patients after laparoscopic procedures: a meta-analysis.

    • Muhammad Shafique Sajid, Ali Sameer Mallick, Jasmin Rimpel, Syed Awais Bokari, Elizabeth Cheek, and Mirza Khurrum Baig.
    • Department of Colorectal Surgery, Worthing Hospital, Worthing, West Sussex, UK. surgeon1wrh@hotmail.com
    • Surg Laparosc Endosc Percutan Tech. 2008 Dec 1;18(6):539-46.

    ObjectiveTo systematically analyze the role of heated humidified carbon dioxide (CO2) in laparoscopy.MethodsClinical trials on laparoscopic procedures using standard dry CO2 versus heated humidified CO2 for pneumoperitoneum were analyzed.ResultsTen randomized controlled trials on 565 patients were analyzed. In both the fixed and random effect models, postoperative pain was significantly less in heated humidified CO2 group. Heated humidified CO2 group was also associated with significantly lower risk of hypothermia and lower analgesic requirement. However, statistically there was no difference in total hospital stay and lens fogging rate.ConclusionsThe use of heated humidified CO2 for pneumoperitoneum in laparoscopic procedures is associated with lesser postoperative pain, lower risk of postoperative hypothermia, and lower analgesic requirements. However, total hospital stay and lens fogging rates do not differ. Hence, the heated and humidified CO2 may be considered as the first choice for pneumoperitoneum in laparoscopic procedures.

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