• J S Afr Vet Assoc · Sep 1998

    Case Reports

    Ketamine hydrochloride--an adjunct for analgesia in dogs with burn wounds.

    • K Joubert.
    • Department of Surgery, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
    • J S Afr Vet Assoc. 1998 Sep 1;69(3):95-7.

    AbstractThe management of pain in patients with burn wounds is complex and problematic. Burn-wound pain is severe, inconsistent and underestimated. Patients experience severe pain, especially during procedures, until wound healing has occurred. A multi-modality approach is needed for effective management of pain, which requires an understanding of the mechanisms of pain. Altered pharmacokinetics and pharmacodynamics in burn-wound patients makes drug actions unpredictable. Opioids alone are seldom sufficient for pain control. The multi-modality approach includes the use of opioids and non-steroidal anti-inflammatory, anxiolytic and alternative drugs. Ketamine has been found to be a useful agent for analgesia in burn-wound patients; a dose of 10 mg/kg qid per os was found to be an effective adjunct to pain therapy.

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