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Randomized Controlled Trial Comparative Study
Comparison of ropivacaine and lidocaine with epinephrine for infiltration anesthesia in dentistry. A randomized study.
- Tadeusz Faustyn Krzemiński, Łukasz Gilowski, Rafał Wiench, Iwona Płocica, Piotr Kondzielnik, and Andrzej Sielańczyk.
- Department of Pharmacology, Medical University of Silesia, Jordana 19, 41-808 Zabrze, Poland.
- Am J Dent. 2011 Oct 1;24(5):305-9.
PurposeTo compare the efficacy of maxillary infiltration anesthesia with 0.5% plain ropivacaine or 2% lidocaine with epinephrine 1:100,000.Methods60 volunteers received 1.8 ml of the anesthetic for infiltration anesthesia of maxillary central and lateral incisors and canine teeth. The onset time and duration of pulp anesthesia were assessed with an electric pulp tester. The duration time of numbness of the upper lip was also monitored. Blood pressure and heart rate were measured before and after administration of the solution.ResultsThe efficacy of anesthesia of the lateral and central incisors was 100% for both anesthetics. There were small insignificant differences in effectiveness of canine pulp anesthesia. The mean onset time was significantly shorter for ropivacaine--2.2 minutes vs. 5.1 for lidocaine. Ropivacaine also had a significantly longer duration of action--mean time 79.2 minutes. Ropivacaine caused statistically significant increases in blood pressure and heart rate.
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