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Orthop. Clin. North Am. · Oct 2015
ReviewLiposomal Bupivacaine: A Comparative Study of More Than 1000 Total Joint Arthroplasty Cases.
- John W Barrington, Oluseun Olugbode, Scott Lovald, Kevin Ong, Heather Watson, and Roger H Emerson.
- Plano Orthopedic Sports Medicine & Spine Center, 5228 W Plano Pkwy, Plano, TX 75093, USA.
- Orthop. Clin. North Am. 2015 Oct 1;46(4):469-77.
AbstractPain after total joint arthroplasty (TJA) can be severe and difficult to control. A single-dose local analgesic delivers bupivacaine in a liposomal time-release platform. In 2248 consecutive patients with hip and knee arthroplasty, half (Pre) were treated using a well-established multimodal analgesia, including periarticular injection (PAI), and half had the PAI substituted for a liposomal bupivacaine injection technique (Post). Pain scores were significantly lower for patients in the Post group for both hip and knee procedures. A large series of patients who had TJA experienced pain relief after the introduction of liposomal bupivacaine as part of an established multimodal protocol.Copyright © 2015 Elsevier Inc. All rights reserved.
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