• Voprosy onkologii · Jan 2004

    Clinical Trial Controlled Clinical Trial

    [Criteria for suppressive dosage of thyroxine administered in thyroid cancer].

    • I M Khmara, Iu E Demidchik, and M N Shapet'ko.
    • Vopr Onkol. 2004 Jan 1;50(5):580-4.

    AbstractThe investigation was concerned with thyroxine therapy for suppression of thyrotrophin synthesis in 1,033 out of 1,544 (66.9%) patients treated for papillary thyroid cancer (hemithyroidectomy--429, thyroidectomy--1,115; 484 of the latter group received radioiodinetherapy postoperatively). Thyroxine 2-5.2 mg/body mass unit was administered for 1-10 yrs (average--4. yrs). Effective daily dose depended on extent of surgery: higher dosage was required after thyroidectomy than hemithyroidectomy, and it was significantly higher after radioiodinetherapy. Bringing thyrotrophin synthesis levels down to normal was necessary in a study based on body mass and height characteristics. Also, an inverse relationship was established between suppressive dose and age. Male patients appeared to require more thyroxine per day than women. Suppressive dosage of thyroxine with regard to age, sex and treatment modality is suggested.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…