• Middle East Afr J Ophthalmol · Oct 2012

    Comparative Study

    The short to medium-term risks of intracameral phenylephrine.

    • Gwyn S Williams, Mahmoud Radwan, Shwan Kadare, and Christopher P R Williams.
    • Department of Ophthalmology, Singleton Hospital, Swansea, Wales, UK.
    • Middle East Afr J Ophthalmol. 2012 Oct 1;19(4):357-60.

    PurposeTo compare outcomes and complications of patients undergoing phacoemulsification with and without the administration of intracameral phenylephrine.Materials And MethodsIn this retrospective study, a chart review was performed. Two groups with an equal number of patients who did or did not receive intracameral phenylephrine during phacoemulsification were compared for differences in outcomes, risk factors and complications. The Chi-square test was used for comparison between groups. P<0.05 was statistically significant.ResultsThe two groups were well matched with regard to preoperative ophthalmic and systemic risk factors for complications and had very similar phacoemulsification power and time profiles. No differences in outcome were detected (P>0.05, all comparisons).ConclusionThis retrospective study suggests that intracameral phenylephrine normalizes the intraoperative risk of small pupil cataract surgery and is not associated with an increased risk of systemic or postoperative ophthalmic complications.

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