• Vet Anaesth Analg · Jul 2007

    Randomized Controlled Trial Comparative Study

    Use of laryngeal mask airway compared to endotracheal tube with positive-pressure ventilation in anesthetized swine.

    • Pamela J Fulkerson and Scott B Gustafson.
    • Magruder Hall, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA. pam.fulkerson@oregonstate.edu
    • Vet Anaesth Analg. 2007 Jul 1;34(4):284-8.

    ObjectiveTo compare the ease of placement and ventilatory parameters of a laryngeal mask airway (LMA) with an endotracheal tube (ETT) in anesthetized swine during positive-pressure ventilation (PPV).Study DesignProspective, randomized, experimental trial.AnimalsNine young domestic swine, weighing between 40 and 49 kg (mean 45.1 kg), being used for a separate terminal surgical study.MethodsThe pigs were immobilized with tiletamine/zolazepam, 2.7-3.6 mg kg(-1), intramuscularly, followed by isoflurane in oxygen delivered by facemask. The lungs were mechanically ventilated through an ETT or an LMA, in random order, during the anesthetic period. Positive-pressure ventilation was adjusted to maintain end-tidal CO2 (Pe'CO2) between 35 and 45 mmHg, with peak inspiratory pressure (P(insp)) of 15-23 cmH2O. Buprenorphine, 0.3 mg intramuscularly, was given to each pig after instrumentation. Isoflurane vaporizer settings were adjusted to maintain a surgical plane of anesthesia. Respiratory rate (RR), tidal volume (V(T)), minute volume (V(E)), and Pe'CO2 were measured and recorded at 5-minute intervals. After the collection of 1 hour of data, the alternate airway was placed. Swine were given at least 30 minutes to stabilize and another hour of data were recorded. At the time of airway placement, the ease of placement was assessed based on time and the number of personnel required. Data were analyzed using paired Student's t-test or Wilcoxon signed rank test where appropriate.ResultsLaryngeal mask airways were significantly easier to place than ETT. Values for V(T) and V(E) were not significantly different between treatments. Peak inspiratory pressures were higher in ETT-ventilated swine.Conclusions And Clinical RelevanceAn LMA may be used as an alternative to an ETT in mechanically-ventilated anesthetized swine. Use of an LMA may reduce time and personnel required for placement of an airway.

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