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Anesthesia and analgesia · Jun 2004
Case ReportsChange in bispectral index during epileptiform electrical activity under sevoflurane anesthesia in a patient with epilepsy.
- Mieko Chinzei, Shigehito Sawamura, Masakazu Hayashida, Takayuki Kitamura, Hisayoshi Tamai, and Kazuo Hanaoka.
- Surgical Centre, Graduate School of Medicine, The University of Tokyo Hospital 113-8655, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan. mieko@bme.rcast.u-tokyo.ac.jp
- Anesth. Analg. 2004 Jun 1; 98 (6): 1734-6, table of contents.
UnlabelledWe observed abnormal fluctuation in Bispectral Index (BIS) caused by repeated alternations between two electroencephalographic (EEG) waveform patterns in a patient with a recent history of epileptic seizure under sevoflurane anesthesia. The repetitive development of the abnormal EEG changes (slow delta with or without spike) and the fluctuation in BIS disappeared almost immediately after administration of anticonvulsants. BIS may give useful information not only on the sedative-hypnotic state, but also on the development of and recovery from abnormal epileptiform EEG activity.ImplicationsDuring epileptiform electroencephalographic activity (EEG), the Bispectral Index shows an abnormal fluctuation caused by repeated abrupt alterations between normal EEG and abnormal epileptiform EEG patterns.
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