• Wariya Sukhupragarn, Prangmalee Leurcharusmee, and Thitipan Sotthisopha.
• J Med Assoc Thai. 2015 Apr 1;98(4):388-93.

ObjectiveTo compare changes of heart rate and blood pressure in patients that underwent LMA anesthesia with VIMA or TIVA technique.Material And MethodA hundred healthy patients, age 16 to 60 years were enrolled. They were randomized into two groups. Patients in group V (VIMA) were induced with 8% sevoflurane until loss of eyelash reflexes then controlled ventilation for five minutes before LMA insertion. Group T (TIVA) patients were given propofol to reach the affected site concentration of eight mcg/mlfor the LMA insertion. Bloodpressure and heart rate were recorded before induction, immediately before and after LMA insertion then every two minutes until surgical incision.ResultsDecreased SBP from baseline in group T was significantly more than group V in each period of time (D1-D7). DBP in group T decreased more than group V significantly only at eight and ten minutes after LMA insertion. The incidence of decreasing SBP > 20% from baseline was more significant in group T than group V. No significant difference of changed HR was found. Coughing during LMA insertion occurred in eight patients (16%) in group T and in three patients (6%) in group V (p = 0.11).ConclusionInduction with propofol by effective site concentration of eight mcg/ml significantly decreased SBP more than with 8% sevoflurane. Both techniques provided smooth LMA insertion without serious complication.

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