• Transplant. Proc. · Oct 2012

    Review Practice Guideline

    Guidelines for maintenance of adult patients with brain death and potential for multiple organ donations: the Task Force of the Brazilian Association of Intensive Medicine the Brazilian Association of Organs Transplantation, and the Transplantation Center of Santa Catarina.

    • G A Westphal, M Caldeira Filho, A Fiorelli, K D Vieira, V Zaclikevis, M Bartz, R Wanzuita, C Teixeira, C Franke, F O Machado, G Friedman, J Andrade, J D Matos, D M Lamgaro, E Silva, G Costa, M E Coelho, M C Oliveira, N C M Youssef, N Akamine, P Duarte, R Lisboa, M Mazzali, B H Ferraz Neto, and Task Force of the Brazilian Association of Intensive Medicine, Brazilian Association of Organs Transplantation, Transplantation Center of Santa Catarina.
    • Brazilian Association of Intensive Medicine, the Brazilian Association of Organ Transplants (ABTO), and the Transplantation Center of Santa Catarina (SC-Tx), Santa Catarina, Brazil.
    • Transplant. Proc. 2012 Oct 1;44(8):2260-7.

    IntroductionThe organ shortage for transplantation, the principal factor that increases waiting lists, has become a serious public health problem. In this scenario, the intensivist occupies a prominent position as one of the professionals that first has a chance to identify brain death and to be responsible for the maintenance of the potential deceased donor.ObjectiveThis report attempts to establish guidelines for care and maintenance of adult deceased donor organs guiding and standardizing care provided to patients with brain death.MethodThese guidelines were composed by intensivists, transplant coordinators, professionals from various transplant teams, and used transplant center. The formulated questions were forwarded to all members and recommendations were constructed after an extensive literature review selecting articles with the highest degree of evidence.ResultsGuidelines were developed in the form of questions reflecting frequent experiences in clinical intensive care practices. The main questions were: Is there an optimal interval for keeping organs of deceased donors viable? What actions are considered essential for maintaining deceased donors in this period? What are the limits of body temperature? How should the patient be warmed? Which laboratory tests should be performed? What is the collection interval? What are the limits in the laboratory and the capture scenario? What are the limits of blood pressure? When and how should one use catecholamines?ConclusionsThis pioneer project involved a multidisciplinary team working in organ transplantation seeking to provide treatment guidance to increase the number of viable organs from deceased adult donors.Copyright © 2012 Elsevier Inc. All rights reserved.

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