• Arch. Bronconeumol. · Feb 2003

    Case Reports

    [Acute non-cardiogenic pulmonary edema secondary to hydrochlorothiazide therapy].

    • B Jara Chinarro, J de Miguel Díez, J L García Satue, M A Juretschke Moragues, and J A Serrano Iglesias.
    • Servicio de Neumología. Hospital Universitario de Getafe. Getafe. Madrid. Spain. beat1089@separ.es
    • Arch. Bronconeumol. 2003 Feb 1;39(2):91-3.

    AbstractSeveral commonly prescribed drugs can cause acute non-cardiogenic pulmonary edema. A cause-effect relationship is usually difficult to establish because symptoms are not specific. We report a case of pulmonary edema induced by a common diuretic, hydrochlorothiazide. This complication can occur after a first dose of the drug or in patients who have been taking it with no side effects. Edema is due to an idiosyncratic reaction rather than an immune response. The clinical course is usually favorable over the first 24 hours with treatment of blood pressure and respiratory support. Given that severity increases with recurrence, we underline the importance of diagnosis in the first episode.

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