• Clin. Orthop. Relat. Res. · Jul 2006

    Case Reports

    Case reports: polymethylmethacrylate lung embolus after limb-salvage surgery of the distal femur.

    • Najat C Daw, Jesse J Jenkins, M Beth McCarville, Bhaskar N Rao, and Michael N Neel.
    • Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. najat.daw@stjude.org
    • Clin. Orthop. Relat. Res. 2006 Jul 1;448:252-6.

    AbstractLimb-salvage surgery for malignant tumors frequently involves reconstruction with an endoprosthesis anchored to bone by using third-generation cementing techniques. A 10-year-old boy with osteosarcoma had a pulmonary embolus caused by polymethylmethacrylate after having limb-salvage surgery that used high-pressure cementing techniques. He experienced transient postoperative chest pain, and a new wedge-shaped radiodense pulmonary lesion appeared on a computed tomography scan of the chest. A thoracotomy for resection of suspected metastatic osteosarcoma revealed a pulmonary infarct caused by cement embolization. Awareness of this potential complication should prompt investigation of possible pulmonary embolism and may prevent unnecessary thoracotomy.

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