• J Emerg Med · Mar 1990

    Case Reports

    "Cotton fever": a benign febrile syndrome in intravenous drug abusers.

    • D W Harrison and R M Walls.
    • Department of Emergency Medicine, Vancouver General Hospital, British Columbia, Canada.
    • J Emerg Med. 1990 Mar 1;8(2):135-9.

    AbstractCotton fever is a benign, self-limited syndrome that may mimic sepsis in intravenous drug addicts. We present an illustrative case and a review of the literature. Serious illness such as pneumonia and infectious endocarditis must always be considered in febrile addicts. However, trivial illness accounts for 16% to 26% of such fevers. Recent evidence suggests that emergency physicians are able to diagnose trivial illness with 93% specificity in febrile adult drug addicts. Short-term observation units may be an alternative to hospital admission for febrile drug users with a presumptive diagnosis of trivial illness and in those in whom the diagnosis of cotton fever is entertained.

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