• J Orthop Trauma · Sep 2014

    Observational Study

    Factors associated with pelvic fracture-related arterial bleeding during trauma resuscitation: a prospective clinical study.

    • Laszlo Toth, Kate L King, Benjamin McGrath, and Zsolt J Balogh.
    • Department of Traumatology, Division of Surgery, John Hunter Hospital and University of Newcastle, Newcastle, New South Wales, Australia.
    • J Orthop Trauma. 2014 Sep 1;28(9):489-95.

    ObjectivesTo determine predictors of pelvic fracture-related arterial bleeding (PFRAB) from the information available in the Emergency Department (ED).DesignProspective cohort study.SettingSingle level-1 Trauma Center.PatientsIn a 3-year period ending in December 2008, consecutive high-energy pelvic fracture patients older than 18 years were included. Patients who arrived >4 hours after injury or dead on arrival were excluded. Patient management followed advanced trauma life support and institutional guidelines. Collected data included patient demographics, mechanism of injury, vital signs, acid-base status, fluid resuscitation, trauma scores, fracture patterns, procedures, and outcomes. Potential predictors were identified using standard statistical tests: Univariate analysis, Pearson correlation (r), receiver operator characteristic, and decision tree analysis.InterventionObservational study.Outcome MeasuresPFRAB was determined based on angiography or computed tomography angiogram or laparotomy findings.ResultsOf the 143 study patients, 15 (10%) had PFRAB. They were significantly older, more severely injured, more hypotensive, more acidotic, more likely to require transfusions in the ED, and had higher mortality rate than non-PFRAB patients. No single variable proved to be a strong predictor but some had a significant correlation with PFRAB. Useful predictors identified were worst base deficit (BD), receiver operator characteristic (0.77, cutoff: 6 mmol/L, r = 0.37), difference between any 2 measures of BD within 4 hours (ΔBD) >2 mmol/L, transfusion in ED (yes/no), and worst systolic blood pressure <104 mm Hg. Demographics, injury mechanism, fracture pattern, temperature, and pH had poor predictive value.ConclusionsBD <6 mmol/L, ΔBD >2 mmol/L, systolic blood pressure <104 mm Hg, and the need for transfusion in ED are independent predictors of PFRAB in the ED. These predictors can be valuable to triage blunt trauma victims for pelvic hemorrhage control with angiography.Level Of EvidencePrognostic Level I. See Instructions for Authors for a complete description of levels of evidence.

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