• Vojnosanit Pregl · May 2012

    Comparative Study Controlled Clinical Trial

    [Assessment of ropivacaine postoperative analgesic effect after periapical maxillary incisors surgery].

    • Milos Tijanić, Nikola Burić, Goran Jovanović, Simona Stojanović, and Milan Spasić.
    • Odeljenje oralne hirurgije, Klinika za stomatologiju, Medicinski fakultet, Univerzitet u Nisu, Nis, Srbija. tijanicm@yahoo.com
    • Vojnosanit Pregl. 2012 May 1;69(5):405-8.

    Background/AimRopivacaine is a relatively new long-acting local anesthetic. The aim of this study was to compare the postoperative analgesic effect of topical anesthetics ropivacaine 0.75% and lidocaine 2% with adrenaline in the postoperative treatment of periapical lesions in the maxilla.MethodsThe study was conducted on 60 subjects, divided into two groups. The study-group received 0.75% ropivacaine without a vasoconstrictor, while the control group was treated with 2% lidocaine with adrenaline (1 : 80.000). Block anesthesia for n. infraorbitalis was used and local anesthetics were applied also on the palatine side for the end branches of n. nasopalatinus. The following parameters were observed: time elapsed from the application of an anesthetic until the first occurrence of pain after the surgery and first intake of an analgesic, the intensity of initial pain, pain intensity 6 h after the application of anesthetics and the total number of analgesics taken within 24 h after the completion of surgery.ResultsThe pain appeared statistically significantly earlier in the patients who had been given lidocaine with adrenaline (p < 0.001), while statistically significantly higher mean values of initial postoperative pain (p < 0.05) and pain intensity 6 h after the intervention (p < 0.01) were also registered in the same group of patients. In the period of 24 h upon the intervention, the study-group patients were taking less analgesics as compared to the control-group subjects (46.6% vs 73.3%), who were given analgesics earlier, although no statistically significant differences were observed related to the number of analgesic doses taken.ConclusionThe results of our study indicate a better postoperative analgesic effect of ropivacaine as compared to lidocaine with adrenaline.

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