• Anesthesia and analgesia · Sep 2013

    Case Reports

    Case report: quetiapine and refractory hypotension during general anesthesia in the operating room.

    • Katherine A Poole, Nina Weber, and Michael Aziz.
    • OHSU, 3181 SW Sam Jackson Park Road, Portland, OR 97239. kpcrna@gmail.co.
    • Anesth. Analg.. 2013 Sep 1;117(3):641-3.

    AbstractQuetiapine is an atypical antipsychotic with known α-adrenergic antagonism. We present a case of refractory hypotension that occurred after induction of general anesthesia in a patient being treated with quetiapine. This patient was not currently taking antihypertensives and had no known cardiovascular abnormalities. We observed that the hypotension was most responsive to vasopressin. We recommend further investigation regarding the interaction of quetiapine and general anesthesia.

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