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Letter Case Reports
Kounis syndrome secondary to amoxicillin/clavulanic acid use.
- Yusuf Tavil, Murat Turfan, Sedat Türkoğlu, and Adnan Abaci.
- Int. J. Cardiol. 2008 Feb 20;124(1):e4-7.
AbstractMyocardial injury and acute coronary syndrome have been rarely associated with amoxicillin/clavulanic acid intake. The responsible pathogenetic mechanism is described by an amplified mast cell degranulation inducing coronary artery spasm and/or acute myocardial infarction in susceptible individuals which is called Kounis syndrome. We report here a case of Kounis syndrome presented with acute coronary syndrome due to amoxicillin/clavulanic acid use. All other etiologies, including ischemic reinfarction were appropriately ruled out.
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