• Arch Pediatr · Feb 2001

    Clinical Trial

    [Analgesia with oxygen-nitrous oxide mixture during percutaneous renal biopsy in children].

    • C Piétrement, R Salomon, F Monceaux, C Petitjean, and P Niaudet.
    • Service de néphrologie pédiatrique, hôpital Necker-Enfants-Malades, 149, rue de Sèvres, 75743 Paris, France.
    • Arch Pediatr. 2001 Feb 1;8(2):145-9.

    UnlabelledThe efficacy of an inhaled equimolar mixture of nitrous oxide and oxygen (Entonox/MEOPA) to prevent procedural pain during renal percutaneous biopsies in children was assessed.Patients And MethodsOne hundred and seven children who underwent 113 renal biopsies during a 17-month period were included in a prospective uncontrolled pediatric study. Efficacy was evaluated using patients' answers to a questionnaire and nurses' observations.ResultsPain was absent in 86.5% of the cases. Mild adverse events were noted in one-third of the procedures, and were always reversible within a few minutes when the inhalation stopped. Acceptability was good. The use of this gas is easy and safe provided a few precautions are observed.ConclusionInhaled equimolar mixture of nitrous oxide and oxygen prevents procedural pain during renal percutaneous biopsies.

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