Caesarean delivery in a parturient with Holt-Oram syndrome and

Arch. Gynecol. Obstet. · Jul 2009

Case Reports

Caesarean delivery in a parturient with Holt-Oram syndrome and implantable cardioverter defibrillator: anaesthetic considerations.

Holt-Oram syndrome is a rare autosomal dominant disorder characterized by skeletal upper-limb dysplasias and congenital cardiac defects. Clinical manifestations of this syndrome vary, and range from sub clinical radiologic findings to overt, life-threatening disease. ⋯ Concerns with regards to anaesthetic management include problems with vascular access, possible arrhythmias, the presence of an AICD, and the possibility of cardiovascular instability. The characteristics of this syndrome and anaesthetic implications are discussed.

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- Senthil K Kanniah.
- Department of Anaesthesia, Altnagelvin Area Hospital, Glenshane Road, Londonderry BT47 6SB, Northern Ireland, UK. s_enthil@yahoo.com
- Arch. Gynecol. Obstet. 2009 Jul 1;280(1):111-3.
AbstractHolt-Oram syndrome is a rare autosomal dominant disorder characterized by skeletal upper-limb dysplasias and congenital cardiac defects. Clinical manifestations of this syndrome vary, and range from sub clinical radiologic findings to overt, life-threatening disease. The author of this article reports safe and effective use of low dose sequential combined spinal and epidural anaesthesia for caesarean section in a parturient with Holt-Oram syndrome and automatic implantable cardioverter defibrillator (AICD). Concerns with regards to anaesthetic management include problems with vascular access, possible arrhythmias, the presence of an AICD, and the possibility of cardiovascular instability. The characteristics of this syndrome and anaesthetic implications are discussed.

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Caesarean delivery in a parturient with Holt-Oram syndrome and implantable cardioverter defibrillator: anaesthetic considerations.

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