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J Bone Joint Surg Br · May 1991
Comparative Study Clinical TrialChymopapain versus conventional surgery for lumbar disc herniation. 10-year results of treatment.
- G D Tregonning, E E Transfeldt, J A McCulloch, I Macnab, and A Nachemson.
- St Michael's Hospital, Toronto, Ontario, Canada.
- J Bone Joint Surg Br. 1991 May 1;73(3):481-6.
AbstractWe reviewed two comparable groups of patients who had been treated for lumbar disc herniation by chymopapain chemonucleolysis (145) or conventional surgical discectomy (91). They were reviewed 10 years after treatment by questionnaire, followed by a personal interview by an independent observer. The results of the surgically treated groups were slightly better than those treated with chymopapain. In particular, there was significantly better early relief of leg and low back pain, and fewer patients needed a second procedure. Complications were few in both groups.
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