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- L Seipel and V Kühlkamp.
- Abteilung Innere Medizin III, Medizinische Universitätsklinik, Tübingen.
- Ther Umsch. 1992 Aug 1;49(8):536-42.
AbstractAll types of antiarrhythmic drugs are suitable for the treatment of junctional and AV-reentry Tachycardias. Betablocker, calcium antagonist and digitalis are mainly influencing the conductivity in the AV node, leaving other structures unaltered. In contrast, class-antiarrhythmic drugs slow conduction and prolong the refractor effect in the accessory pathway. In addition, drugs of subclass 1c can influence especially the 'fast' pathway in dual AV-node conduction. Class-3 drugs prolong refractoring in all compartments of the heart by preventing re-entry in both, AV nodal tachycardias and AV re-entry in the WPW syndrome. The clinical indication for one of these drugs is mainly influenced by the potential side-effects and by pharmacokinetic considerations.
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