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Randomized Controlled Trial Clinical Trial
Femoral nerve block and ketorolac in patients undergoing anterior cruciate ligament reconstruction.
- P Peng, A Claxton, F Chung, V Chan, A Miniaci, and A Krishnathas.
- Department of Anesthesia, Toronto Hospital, University of Toronto, Ontario, Canada. ppeng@torhosp.toronto.on.ca
- Can J Anaesth. 1999 Oct 1; 46 (10): 919924919-24.
PurposeThe primary objective was to evaluate the analgesic effectiveness of femoral nerve block and ketorolac following ACL reconstruction. The secondary objective was to examine their effects on recovery milestones.MethodsPrior to standard general anesthesia, 90 patients were randomized into three groups of preoperative treatment: 1) femoral nerve block (15 mL bupivacaine 0.5%) and 1 mL normal saline i.v. (FNB group); 2) placebo femoral nerve block (15 mL normal saline) and 30 mg (1 mL) ketorolac i.v. (KT group); 3) placebo femoral nerve block (15 mL normal saline) and 1 mL normal saline i.v. (PL group). Postoperatively, pain was assessed by visual analogue score, demand and consumption of morphine via patient-controlled analgesia pump. The times for patients to tolerate oral fluid, food, sit up, ambulate and void were also noted.ResultsMorphine consumption within one hour, three hours and until POD 1 in the FNB group was lower than the PL group (7 +/- 6, 11 +/- 9, 27 +/- 23 mg vs 13 +/- 5, 20 +/- 9, 49 +/- 28 mg respectively), whereas only that within one hour in the KT group was lower than the PL group. Pain score was lower in FNB and KT groups in the first postoperative hour than in the PL group (P < 0.05). There were no differences among the three groups in the times to meet recovery milestone and discharge criteria.ConclusionFemoral nerve block provides superior analgesia than placebo for ACL reconstruction but was insufficient to facilitate early recovery.
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