• Clin. Appl. Thromb. Hemost. · Aug 2010

    Ultrastructural and morphological analyses of the in vitro and in vivo hemostatic effects of Ankaferd Blood Stopper.

    • Berat Z Haznedaroglu, Ibrahim C Haznedaroglu, Sharon L Walker, Hasan Bilgili, Hakan Goker, Ali Kosar, Alper Aktas, Ozge Captug, Mevlut Kurt, Oktay Ozdemir, Serafettin Kirazli, and Huseyin C Firat.
    • Department of Chemical and Environmental Engineering, University of California, Riverside, California, USA.
    • Clin. Appl. Thromb. Hemost. 2010 Aug 1;16(4):446-53.

    AbstractUltrastructural and morphological analyses of a novel hemostatic agent, Ankaferd Blood Stopper (ABS), in comparison to its in vitro and in vivo hemostatic effects were investigated. High-resolution scanning electron microscopy (SEM) images accompanied with morphological analysis after topical application of ABS revealed a very rapid (<1 second) protein network formation within concurrent vital erythroid aggregation covering the classical coagulation cascade. Histopathological examination revealed similar in vivo ABS-induced hemostatic network at the porcine hepatic tissue injury model. Instantaneous control of bleeding was achieved in human surgery-induced dental tissue injury associated with primary and secondary hemostatic abnormalities. Ankaferd Blood Stopper could hold a great premise for clinical management of surgery bleedings as well as immediate cessation of bleeding on external injuries based on upcoming clinical trials.

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