• Zentralbl Gynakol · Jan 1989

    Case Reports

    [Spontaneous post-partum inhibitor to factor VIII clotting anti- gen--a cause of life-threatening hemorrhage].

    • G Lutze, E Canzler, and H J Presser.
    • Institut für Klinische Chemie und Laboratoriumsdiagnostik, Medizinischen Akademie Magdeburg.
    • Zentralbl Gynakol. 1989 Jan 1;111(3):167-72.

    AbstractPathologic inhibitors of blood coagulation as cause of acquired haemostatic failure are rare. We report about a 23 years old primigravida with a life-threatening haemorrhage post partum. Analysis of coagulation parameters showed the presence of inhibitor to factor VIII. We reacted successfully with cyclophosphamid and cryoprecipitated factor VIII. References to diagnostic and therapy of pathologic clotting factor inhibitors are described.

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