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Anesthesia and analgesia · May 2009
Case ReportsPostoperative intensive care unit drug fever caused by dexmedetomidine.
- Tadashi Okabe, Shinhiro Takeda, Shinji Akada, Takashi Hongo, and Atsuhiro Sakamoto.
- Department of Anesthesiology and Intensive Care Medicine, Nippon Medical School, Tokyo, Japan.
- Anesth. Analg. 2009 May 1;108(5):1589-91.
AbstractDexmedetomidine hydrochloride is a potent, highly selective alpha-2 adrenergic receptor agonist, broadly used as a sedative drug in intensive care units. We describe the case of a 59-yr-old patient who experienced drug fever caused by dexmedetomidine hydrochloride. The patient was transferred to the intensive care unit with an abdominal aortic aneurysm rupture. After initiation of sedation with dexmedetomidine hydrochloride, he developed pyrexia of more than 39 degrees C. This symptom improved rapidly 7 h after stopping dexmedetomidine hydrochloride. Other possible causes (such as infection) were sequentially eliminated.
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