• Ismail Serhat Kocamanoglu, Elif Bengi Sener, Emre Ustun, and Ayla Tur.
• Department of Anaesthesiology, Faculty of Medicine, University of Ondokuz Mayis, Samsun, Turkey. serhatk@omu.edu.tr
• Laryngoscope. 2006 Jan 1;116(1):23-7.

Objective/HypothesisThe aim of this study is to compare the effects of lidocaine and methylprednisolone on postoperative respiratory complications caused by short-term laryngeal surgery by way of rigid laryngoscope under general anesthesia. The effects of these drugs on recovery from anesthesia are also compared.Study DesignOne hundred American Society of Anesthesiologists physical status I to II patients over 20 years of age admitted for laryngeal mass, nodule, or polyp were included in this prospective, placebo-controlled, randomized, and double-blinded study.MethodsPatients were randomly allocated to four groups; methylprednisolone 3 mg.kg-1 (group 1), 0.9% saline physiologic 5 mL (group 2), lidocaine 1.5 mg.kg-1 (group 3) intravenously, seven puffs of lidocaine aerosol 10% to oropharyngolaryngeal structures topically (group 4) sprayed. Anesthesia recovery time was calculated. Respiratory system was evaluated using a scoring table during early postoperative period.ResultsNinety-two cases were suitable for analysis. Recovery time was longer in group 1 (9.8 3+/- 3.79 minutes) than in groups 3 and 4 (7.22 +/- 2.38, 7.50 +/- 2.30 minutes, respectively) (P < .05). Postoperative respiratory complications were lower in groups 3 and 4 than group 2 (P < .05).ConclusionsLidocaine intravenous or topical administration was effective in reducing postoperative respiratory complications after short-term laryngeal surgery by way of rigid laryngoscope. Methylprednisolone prolonged recovery time from anesthesia.

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