• Hum Exp Toxicol · Dec 2011

    Case Reports

    Dialysis therapy for lactic acidosis caused by metformin intoxication: presentation of two cases.

    • Yasemin Usul Soyoral, Huseyin Begenik, Habib Emre, Enver Aytemiz, Mustafa Ozturk, and Reha Erkoc.
    • Department of Nephrology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey. yaseminsoyoral@yahoo.com
    • Hum Exp Toxicol. 2011 Dec 1;30(12):1995-7.

    AbstractMetformin is an oral antidiabetic, which is frequently used in the treatment of type II diabetes mellitus. Serious side effects may be seen during the administration of high doses of metformin. Two cases of lactic acidosis due to ingestion of high dose metformin for suicidal purposes have been presented here; in both cases, clinical improvement was seen with bicarbonate hemodialysis.

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