• Anaesthesia · Apr 2016

    Review

    A systematic review of capnography for sedation.

    • A Conway, C Douglas, and J R Sutherland.
    • Queensland University Technology Institute of Health & Biomedical Innovation, Brisbane, Queensland, Australia.
    • Anaesthesia. 2016 Apr 1; 71 (4): 450-4.

    AbstractWe included six trials with 2524 participants. Capnography reduced hypoxaemic episodes, relative risk (95% CI) 0.71 (0.56-0.91), p = 0.02, but the quality of evidence was poor due to high risks of performance bias and detection bias and substantial statistical heterogeneity. The reduction in hypoxaemic episodes was statistically homogeneous in the subgroup of three trials of 1823 adults sedated for colonoscopy, relative risk (95% CI) 0.59 (0.48-0.73), p < 0.001, although the risks of performance and detection biases were high. There was no evidence that capnography affected other outcomes, including assisted ventilation, relative risk (95% CI) 0.58 (0.26-1.27), p = 0.17. © 2016 The Association of Anaesthetists of Great Britain and Ireland.

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