• K Menif, A Khaldi, A Bouziri, W Kechaou, S Belhadj, A Hamdi, K Kazdaghli, and N Benjaballah.
• Service de réanimation pédiatrique polyvalente, hôpital d'enfants de Tunis, place Bab-Saadoun-Jebbari, Tunis, Tunisie. menifk@yahoo.fr
• Med Mal Infect. 2009 Dec 1;39(12):896-900.

GoalThis study had for aim to determine the mortality rate and the factors affecting mortality among 70 children admitted for septic shock secondary to a community acquired infection.Patients And MethodsA retrospective analysis was made of patients admitted between January 1998 and August 2005, in a pediatric ICU for septic shock secondary to a community-acquired infection. Neonates under 7 days of age were excluded from the study.ResultsSeventy cases were included and 32 (45.7 %) of them died. Their average age was 3.8+/-4.2 years and their PRISM during the first 24 hours was 19.2+/-8.4. Sixty-nine children (98.6 %) presented with multivisceral failure and 60 (85.7 %) with more than two deficient organs. The average time between the observation of first hemodynamic disorders and admission to ICU was 9.4+/-11.3 hours. Three independent mortality risk factors were identified: failure of more than two organs on admission (OR, 4.4; 95 % CI [2.1-9.4]), an infusion volume superior to 20ml/kg on the second day of resuscitation (OR, 3.4; 95 CI % [1.1-10.3]), and the use of more than two vasoactive drugs (OR, 3.3; 95 CI % [1.2-9]).

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