• Pediatric emergency care · Apr 2013

    Case Reports

    Development of pyloric stenosis after a 4-day course of oral erythromycin.

    • Luis E Lozada, Matthew J Royall, Cade M Nylund, and Matthew D Eberly.
    • Department of Pediatrics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
    • Pediatr Emerg Care. 2013 Apr 1;29(4):498-9.

    AbstractEarly exposure to oral erythromycin in young infants, particularly in the first 2 weeks of life, has previously been associated with the development of hypertrophic pyloric stenosis. We report a case of an infant who received an abbreviated 4-day course of oral erythromycin for suspected Chlamydia conjunctivitis at 5 days of life then underwent pyloromyotomy for pyloric stenosis less than 2 weeks later. Health care providers should use erythromycin judiciously in neonates because only a few days of exposure to this medication may lead to the development of a surgical condition of gastric outlet obstruction.

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