Management of platypnea-orthodeoxia syndrome by

J Invasive Cardiol · Oct 2004

Management of platypnea-orthodeoxia syndrome by transcatheter closure of atrial communication: hemodynamic characteristics, clinical and echocardiographic outcome.

Percutaneous transcatheter closure of patent foramen ovale or atrial septal defect is an alternative to surgery for the treatment of platypnea-orthodeoxia syndrome. We report the hemodynamic characteristics and clinical and echocardiographic outcomes of 18 patients with platypnea-orthodeoxia syndrome that underwent transcatheter closure of patent foramen ovale or atrial septal defect. Successful closure was achieved in all patients with no in-hospital mortality or adverse events. Complete resolution of symptoms was seen in all patients and mean oxygen saturation increased from 82.6 +/- 5.4% to 96.1+/-2.2% post-procedure (p < 0.01).

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- Gabriel Delgado, Ignacio Inglessis, Francisco Martin-Herrero, Danita Yoerger, Richard Liberthson, Fernando Buoanno, and Igor Palacios.
- Massachusetts General Hospital, Boston, MA 02114, USA.
- J Invasive Cardiol. 2004 Oct 1;16(10):578-82.
AbstractPercutaneous transcatheter closure of patent foramen ovale or atrial septal defect is an alternative to surgery for the treatment of platypnea-orthodeoxia syndrome. We report the hemodynamic characteristics and clinical and echocardiographic outcomes of 18 patients with platypnea-orthodeoxia syndrome that underwent transcatheter closure of patent foramen ovale or atrial septal defect. Successful closure was achieved in all patients with no in-hospital mortality or adverse events. Complete resolution of symptoms was seen in all patients and mean oxygen saturation increased from 82.6 +/- 5.4% to 96.1+/-2.2% post-procedure (p < 0.01).

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Management of platypnea-orthodeoxia syndrome by transcatheter closure of atrial communication: hemodynamic characteristics, clinical and echocardiographic outcome.

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