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Pediatric emergency care · Apr 2013
Case ReportsFever and bulging fontanelle mimicking meningitis in an infant diagnosed with benign intracranial hypertension.
- Ethan M Goldberg.
- Division of Neurology, The Children's Hospital of Philadelphia, Colket Translational Research Center, Philadelphia, PA 19104-4399, USA. goldberge@email.chop.edu
- Pediatr Emerg Care. 2013 Apr 1;29(4):513-4.
AbstractA previously healthy 7-month-old male presented to the emergency department with fever and a bulging anterior fontanelle. A computed tomographic scan of the head suggested mild communicating hydrocephalus. Lumbar puncture was performed, which revealed a normal cerebrospinal fluid (CSF) cell count and glucose concentration, but a markedly elevated opening pressure. DNA polymerase chain reaction for herpes simplex virus performed on CSF was negative; CSF bacterial cultures were without growth. DNA polymerase chain reaction for human herpes virus 6 was strongly positive in serum. Fever and bulging fontanelle resolved within 24 hours. A presumptive diagnosis of transient intracranial hypertension of infancy was made, a form of benign idiopathic intracranial hypertension that mimics the presentation of serious intracranial pathology.
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