• Br J Anaesth · Mar 2000

    Randomized Controlled Trial Clinical Trial

    Rectally administered dimenhydrinate reduces postoperative vomiting in children after strabismus surgery.

    • A Schlager, G Mitterschiffthaler, and F Pühringer.
    • Department of Anaesthesia and Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria.
    • Br J Anaesth. 2000 Mar 1;84(3):405-6.

    AbstractWe have investigated the effectiveness of rectally administered dimenhydrinate on postoperative vomiting in children undergoing strabismus surgery, in a double-blind, randomized, placebo-controlled study. In one group, dimenhydrinate 50 mg was administered rectally 30 min before starting anaesthesia, whereas in the control group, placebo suppositories were given. Children who received dimenhydrinate showed a significantly (P < 0.001) lower incidence of vomiting (15%) than those in the control group (75%). We conclude that rectal administration of dimenhydrinate is an effective means of reducing postoperative vomiting in children undergoing strabismus surgery.

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