• J. Clin. Invest. · Jul 1970

    Observations on a model of proliferative lung disease. II. Description of pulmonary gas exchange and comparison of Fick and dye cardiac outputs.

    • P R Caldwell, U Echeverri, M M Kilcoyne, and H W Fritts.
    • J. Clin. Invest. 1970 Jul 1;49(7):1311-5.

    AbstractMeasurements of gas exchange in dogs with granulomatous lung disease resembled those which have been made in similar disorders of man. The minute volume of ventilation was large, the oxygen extracted from each liter of ventilation was low, and the arterial blood oxygen saturation tended to be subnormal despite hyperventilation. When the diseased dogs breathed 21% oxygen and had alveolar oxygen tensions above 100 mm Hg, the pulmonary blood flows calculated from the Fick principle were significantly higher than those estimated by the dye-dilution method. By way of contrast, the two values agreed when the alveolar tensions were lowered. Whether the agreement of the flows is causally related to the alveolar tension remains an open question. A possible explanation may lie in the effect of alveolar tension on the oxygen consumed by the diseased lung.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…