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Pediatric emergency care · Jun 2011
Case ReportsSuccessful intravenous thrombolysis in a 14-year-old boy with ischemic stroke.
- Francisco Abecasis, Isabel Sampaio, Sofia Quintas, Cristina Camilo, Marisa Vieira, Teresa Pinho e Melo, and Manuela Correia.
- Pediatrics Department, Hospital de Santa Maria, Lisbon, Portugal. i_sampaio@yahoo.com
- Pediatr Emerg Care. 2011 Jun 1;27(6):541-3.
AbstractWe report a healthy 14-year-old boy with an acute left middle cerebral artery stroke, treated 2 hours after the onset of symptoms with intravenous recombinant tissue plasminogen activator (r-TPA). Recanalization of the middle cerebral artery was documented with transcranial Doppler during the first 5 minutes of intravenous r-TPA perfusion, and progressive recovery of the neurological deficits occurred. Although lack of evidence regarding safety and efficacy in children precludes the recommendation of systematic use of r-TPA in pediatric stroke, we propose that this option should be considered and discussed with the parents, especially in older children presenting within 3 hours in centers with experience in adult thrombolysis.
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