• Expert Rev Anti Infect Ther · Jul 2011

    Review

    Current management of sepsis in critically ill adult patients.

    • Jean-Louis Vincent, Elena Carrasco Serrano, and Aikaterina Dimoula.
    • Department of Intensive Care, Erasme Hospital, Université libre de Bruxelles, Belgium. jlvincen@ulb.ac.be
    • Expert Rev Anti Infect Ther. 2011 Jul 1;9(7):847-56.

    AbstractSevere sepsis is a common occurrence in critically ill patients and a major cause of morbidity and mortality in this population. Management relies on the early identification and treatment of the underlying causative infection, adequate and rapid hemodynamic resuscitation, support of associated organ failure and modulation of the immune response with drotrecogin alfa (activated) when it is not contraindicated, and corticosteroids in severe septic shock. We will review current approaches to each of these categories.

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