• Zhonghua yi xue za zhi · Dec 2011

    Randomized Controlled Trial

    [Propofol target controlled infusion plus a low concentration of sevoflurane inhalation induction anesthesia for the removal of foreign body from tracheobronchus in children].

    • Xu-tong Zhang, Dan-si Qi, Hua-cheng Liu, Er-zhan Su, and Jun Li.
    • Department of Anesthesiology, Second Affiliated Hospital, Wenzhou Medical College, Wenzhou 325027, China.
    • Zhonghua Yi Xue Za Zhi. 2011 Dec 20;91(47):3333-6.

    ObjectiveTo explore the effects of propofol target controlled infusion (TCI) plus a low concentration of sevoflurane inhalation induction for the removal of tracheobronchial foreign body in children.MethodsAfter the approval of the hospital ethics committee, a total of 90 patients, aged 9 - 36 months old and weighted 8 - 17 kg, were randomly divided into 3 groups: group A, group B and group C. Propofol TCI plus a low concentration of sevoflurane inhalation induction was administered in group A while ketamine or fentanyl plus propofol TCI in group B or C respectively. Effects of anesthesia, complications and recovery durations were observed.ResultsThe incidence of severe breathholding and bucking during inserting bronchoscope was 1 case in group A, 7 in group B and 5 in group C. There were significant differences between groups A and B (P < 0.05). The minimal intra-operative SpO2 in group B or group C was lower than that in group A (P < 0.01). The cases for intra-operative SpO2 < 95% in group B or group C were more than that in group A (P < 0.01). And the maximal target concentration of propofol was significantly higher than that in group A (P < 0.01). Ten cases in group B had laryngeal stridor and dyspnea during inspirations post-operatively and occurred more frequently than those in group A or C (P < 0.01). As compared with group A and C, post-operative staying lengths and recovery durations were significantly longer in those in group B (P < 0.01).ConclusionPropofol TCI plus a low concentration of sevoflurane inhalation induction is both safe and practical for the controlled removal of tracheobronchial foreign body in children.

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