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- James C Huhta, Alfred Asante-Korang, Maria Serrano, and Suma Gudur.
- Department of Pediatrics, University of South Florida, Tampa, Florida 33701, USA. huhfam@aol.com
- Curr. Opin. Pediatr. 2005 Oct 1;17(5):563-7.
Purpose Of ReviewBiochemical markers are available to detect cardiac involvement in many pediatric disease states and should be considered.Recent FindingsAnalyses of three markers are readily available in clinical laboratories for improved diagnosis.SummaryIncreased workload of the heart has been associated with the release of biochemical markers (natriuretic peptides and cardiac enzymes) that indicate that a new genetic program has been activated and maladaptation is occurring in the atria, ventricles, or both. This review summarizes those that have been identified in fetal and pediatric practice. The expression of such markers is traced from early embryonic development to fetal life, to the neonate, to childhood, and then to adult life.
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