• Anaesth Intensive Care · Aug 1991

    Clinical Trial Controlled Clinical Trial

    Does propofol have an anti-emetic effect? A prospective study of the anti-emetic effect of propofol following laparoscopy.

    • N N Campbell and A D Thomas.
    • Department of Anaesthetics, Gloucestershire Royal Hospital, Gloucester, England.
    • Anaesth Intensive Care. 1991 Aug 1;19(3):385-7.

    AbstractIn order to investigate the putative anti-emetic effect of propofol, 53 patients undergoing gynaecological laparoscopy were given a standard anaesthetic including induction with thiopentone. At the end of surgery, the patients received either a sub-anaesthetic does of propofol or an equivalent volume of normal saline. There was no difference in the incidence of nausea and vomiting between the propofol and control group. It is concluded that low-dose propofol does not have an anti-emetic effect.

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