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J Comput Assist Tomogr · Nov 2002
Case ReportsTranslocation of Broca's area to the contralateral hemisphere as the result of the growth of a left inferior frontal glioma.
- Andrei I Holodny, Michael Schulder, Albert Ybasco, and Wen-Ching Liu.
- Department of Radiology, University of Medicine and Dentistry of New Jersey-NJ Medical School, Newark, NJ, USA. holodnya@mskcc.org
- J Comput Assist Tomogr. 2002 Nov 1;26(6):941-3.
AbstractWe report a case of a patient with a left inferior frontal glioma in whom language functional magnetic resonance imaging (fMRI) paradigms produced activation of Broca's area on the right and Wernicke's area on the left. We propose that tumor invasion of the left frontal operculum led to cortical reorganization and interhemispheric transfer of Broca's area. This case emphasizes the importance of preoperative fMRI in assessing the location of eloquent cortices adjacent to a tumor and in guiding neurosurgical decision-making.
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