• Elizabeth B Malinzak and Tong J Gan.
• Department of Anesthesiology, Duke University Medical Center, Duke University School of Medicine, Durham, NC 27710, USA.
• Anesth. Analg. 2009 Sep 1;109(3):976-80.

BackgroundApproximately 25% of initial arteriovenous fistula (AVF) placements will fail as a result of thrombosis or failure to develop adequate vessel size and blood flow. Fistula maturation is impacted by patient characteristics and surgical technique, but both increased vein diameter and high fistula blood flow rates are the most important predictors of successful AVFs. Anesthetic techniques used in vascular access surgery (monitored anesthesia care, regional blocks, and general anesthesia) may affect these characteristics and fistula failure.MethodsWe performed a literature search using key words in the PubMed/MEDLINE database. Seven articles that related to the effects of anesthesia on AVF construction, including sympathetic block, vein dilation, blood flow, adverse outcomes, or patency rates, comprised the sources for this review.ResultsSignificant vasodilation after regional block administration is seen in both the cephalic and basilic veins. These vasodilatory properties may assist with AVF site selection. In the intraoperative and postoperative periods, use of a regional block, compared with other anesthetic techniques, resulted in significantly increased fistula blood flow. The greater sympathetic block contributed to vessel dilation and reduced vasospasm. Use of regional techniques in AVF construction yielded shorter maturation times, lower failure rates, and higher patency rates.ConclusionUse of regional blocks may improve the success of vascular access procedures by producing significant vasodilatation, greater fistula blood flow, sympathectomy-like effects, and decreased maturation time. However, a large-scale, prospective, clinical trial comparing the different anesthetic techniques is still needed to verify these findings.

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