• Am. J. Surg. · Jun 2014

    Meta Analysis

    Meta-analysis of sublay versus onlay mesh repair in incisional hernia surgery.

    • Lucas Timmermans, Barry de Goede, Sven M van Dijk, Gert-Jan Kleinrensink, Johannes Jeekel, and Johan F Lange.
    • Department of Surgery, Erasmus MC, University Medical Center, Z-835, 3000 CA Rotterdam, The Netherlands. Electronic address: lucastimmermans@gmail.com.
    • Am. J. Surg. 2014 Jun 1;207(6):980-8.

    BackgroundIncisional hernia (IH) remains a very frequent postoperative complication. The 2 techniques most frequently used are the onlay repair and sublay repair. However, it remains unclear which technique is superior.Data SourcesA meta-analysis was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The quality of the nonrandomized studies was assessed using the Newcastle-Ottawa Scale.ResultsOf 178 articles, 10 articles (2 randomized controlled trials, 1 prospective study, and 7 retrospective studies) comprising a total of 1,948 patients (775 onlay operations and 1173 sublay operations) were selected. Two of the studies scored below 5 points on the Newcastle-Ottawa Scale and were not selected. A trend was observed for IH recurrence in favor of sublay repair (odds ratio = 2.41; 95% confidence interval, .99 to 5.88; I(2) = 70%; P = .05). Surgical site infection occurred significantly less after sublay repair (odds ratio = 2.42; 95% confidence interval, 1.02 to 5.74; I(2) = 16%; P = .05). No difference was observed regarding seroma and hematoma.ConclusionsAlthough the majority of the included studies were retrospective studies, sublay repair seems the preferred technique for IH repair.Copyright © 2014 Elsevier Inc. All rights reserved.

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